Biomarkers for hepatocellular carcinoma: diagnostic and therapeutic utility
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چکیده
منابع مشابه
Biomarkers for hepatocellular carcinoma: diagnostic and therapeutic utility
Because of the high prevalence and associated-mortality of hepatocellular carcinoma (HCC), early diagnosis of the disease is vital for patient survival. In this regard, tumor size is one of the two main prognostic factors for surgical resection, which constitutes the only curative treatment for HCC along with liver transplantation. However, techniques for HCC surveillance and diagnosis that are...
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Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide. The HCC diagnosis is usually achieved by biomarkers, which can also help in prognosis prediction. Furthermore, it might represent certain therapeutic interventions through some combinations of biomarkers. Here, we review on our current understanding of HCC biomarkers.
متن کاملBiomarkers for Hepatocellular Carcinoma
The hepatocellular carcinoma (HCC) is one of the most common malignant tumors and carries a poor survival rate. The management of patients at risk for developing HCC remains challenging. Increased understanding of cancer biology and technological advances have enabled identification of a multitude of pathological, genetic, and molecular events that drive hepatocarcinogenesis leading to discover...
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• Recent advances in genomic, proteomic and metabolomic technologies are enabling the identification of novel biomarkers for hepatocellular carcinoma (HCC). Most of these new markers are currently in phase 1 of biomarker development. • HCC biomarkers are mainly used as screening tools in surveillance programs for early HCC detection, with the ultimate goal of reduction in HCC mortality. Current...
متن کاملan overview of biomarkers for the diagnosis of hepatocellular carcinoma
context primary liver cancer is one of the most common and deadly malignant neoplasms worldwide. the incidence and mortality rates for hepatocellular carcinoma (hcc) are virtually identical, reflecting the poor overall survival of patients with this kind of tumor. effective therapies mostly achieved if the hcc diagnosis is made at early stages of the tumor. surveillance tests include serologic ...
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ژورنال
عنوان ژورنال: Hepatic Medicine: Evidence and Research
سال: 2015
ISSN: 1179-1535
DOI: 10.2147/hmer.s50161